1.社会兼职：

担任江苏省医学会外科学分会委员、江苏省医师协会外科学分会委员、江苏省医学会外科学分会基层学组组长、江苏省抗癌协会理事、江苏省研究性医院学会胃食管反流病专业委员会副主任委员、连云港市抗癌协会理事、连云港市医师协会副会长、连云港市医师协会外科医师分会会长等；

2.研究方向：

胃肠道肿瘤研究

3.主持/参与课题：

（1）江苏省“六大人才高峰”高层次人才资助项目：miR-301在顺铂治疗胃癌耐药中的作用机制研究，2018.10-2021.09，主持

（2）连云港市科技局项目：术前口服麦芽糊精果糖饮品对胃癌患者术后快速康复的影响及其价值，2016.11-2018.10，主持

（3）江苏大学临床医学科技发展基金项目：circNF1通过m6A甲基化修饰促进结直肠癌肝转移的机制研究，2021.6-2023.12，主持

（4）连云港市521工程项目：HNRNPC调节circNF1的m6A甲基化通过ceRNA式作用促进结直肠癌肝转移的机制研究，2021.11-2023.11，主持

（5）江苏省医院协会医院管理创新研究课题：整合医疗视角下消化道早癌诊治模式探讨，2023.7-2025.6，主持

（6）连云港市卫生健康科技项目：RNA去甲基化酶TET1调控SSBP2的m5C修饰促进胃癌发展的机制研究，2023.10-2026.10，主持

4.科技成果：

（1）已发表论文：

[1] Ji T, Cai Y, Gao Y, Wang G, Miao Y, Gao X. Establishment and application of a rapid visual diagnostic method for Streptococcus agalactiae based on recombinase polymerase amplification and lateral flow strips. Sci Rep. 2024 May 2;14(1):10064. doi: 10.1038/s41598-024-56138-7. PMID: 38698011; PMCID: PMC11066032.

[2]Fang G, Xu D, Zhang T, Qiu L, Gao X, Wang G, Miao Y. Effects of hsa_circ_0074854 on colorectal cancer progression, construction of a circRNA-miRNA-mRNA network, and analysis of immune infiltration. J Cancer Res Clin Oncol. 2023 Nov;149(17):15439-15456. doi: 10.1007/s00432-023-05315-8. Epub 2023 Aug 29. PMID: 37644235; PMCID: PMC10620273.

[3] Fang G, Xu D, Zhang T, Wang G, Qiu L, Gao X, Miao Y. Biological functions, mechanisms, and clinical significance of circular RNA in colorectal cancer. Front Oncol. 2023 Mar 6;13:1138481. doi: 10.3389/fonc.2023.1138481. PMID: 36950552; PMCID: PMC10025547.

[4]Qiu L, Yang X, Wu J, Huang C, Miao Y, Fu Z. HIST2H2BF Potentiates the Propagation of Cancer Stem Cells via Notch Signaling to Promote Malignancy and Liver Metastasis in Colorectal Carcinoma. Front Oncol. 2021 Aug 12;11:677646. doi: 10.3389/fonc.2021.677646. PMID: 34476209; PMCID: PMC8406628.

[5] Zhang T, Wang G, Fang G, Qiu L, Lu F, Yin K, Miao Y. Clinical efficacy of anastomotic reinforcement suture in preventing anastomotic leakage after rectal cancer surgery: a systematic review and meta-analysis. Langenbecks Arch Surg. 2023 Aug 18;408(1):322. doi: 10.1007/s00423-023-03058-1. PMID: 37594605.

[6]Wang L, Xu A, Zhou P, Zhao M, Xu C, Wang Y, Wang K, Wang F, Miao Y, Zhao W, Gao X. Rapid Detection of Candida tropicalis in Clinical Samples From Different Sources Using RPA-LFS. Front Cell Infect Microbiol. 2022 Jul 7;12:898186. doi: 10.3389/fcimb.2022.898186. PMID: 35873165; PMCID: PMC9301490.

[7] Miao Y, Zhang X, Chen S, Zhou W, Xu D, Shi X, Li J, Tu J, Yuan X, Lv K, Tian G. Identifying cancer tissue-of-origin by a novel machine learning method based on expression quantitative trait loci. Front Oncol. 2022 Aug 9;12:946552. doi: 10.3389/fonc.2022.946552. PMID: 36016607; PMCID: PMC9396384.

[8] Zhang Q, Miao Y, Fu Q, Hu H, Chen H, Zeng A, Jin Y, Jiang Y, Qian L, Wu L, Xu L, Wang G, Qiu L, Huang X, Xia Y. CircRNACCDC66 regulates cisplatin resistance in gastric cancer via the miR-618/BCL2 axis. Biochem Biophys Res Commun. 2020 Jun 4;526(3):713-720. doi: 10.1016/j.bbrc.2020.03.156. Epub 2020 Apr 3. PMID: 32253030.

[9] Wang G, Zhou J, Lu F, Qiu L, Xu L, Yang X, Miao Y. Downregulation of microRNA 183 5p inhibits the proliferation and invasion of colorectal cancer cells by inactivating the reticulocalbin 2/Wnt/β catenin signaling pathway. Mol Med Rep. 2019 May;19(5):4475-4483. doi: 10.3892/mmr.2019.10059. Epub 2019 Mar 19. PMID: 30896885.

[10]Qiu L, Lu F, Zhang L, Wang G, Geng R, Miao Y. HBXIP Regulates Gastric Cancer Glucose Metabolism and Malignancy Through PI3K/AKT and p53 Signaling. Onco Targets Ther. 2020 Apr 21;13:3359-3374. doi: 10.2147/OTT.S243250. PMID: 32368094; PMCID: PMC7183336.

[11]Miao Y, Li Q, Sun G, Wang L, Zhang D, Xu H, Xu Z. MiR-5683 suppresses glycolysis and proliferation through targeting pyruvate dehydrogenase kinase 4 in gastric cancer. Cancer Med. 2020 Oct;9(19):7231-7243. doi: 10.1002/cam4.3344. Epub 2020 Aug 11. PMID: 32780563; PMCID: PMC7541129.

[12] Lu F, Qiu L, Yu P, Xu DL, Miao YC, Wang G. Application of a three-dimensional printed pelvic model in laparoscopic radical resection of rectal cancer. Front Oncol. 2023 Jun 19;13:1195404. doi: 10.3389/fonc.2023.1195404. PMID: 37404759; PMCID: PMC10315900.

[13]Fang G, Xu D, Zhang T, Wang G, Qiu L, Gao X, Miao Y. Biological functions, mechanisms, and clinical significance of circular RNA in colorectal cancer. Front Oncol. 2023 Mar 6;13:1138481. doi: 10.3389/fonc.2023.1138481. PMID: 36950552; PMCID: PMC10025547.

[14] 张韬,王刚,邱磊,等.加速康复外科在老年结直肠癌患者中的临床研究[J].中国肿瘤外科杂志,2022,14(05):484-488.

[15] 苗永昌,邱磊,邵华,等.BRG1在结肠癌组织中的表达及其临床意义[J].南京医科大学学报(自然科学版),2018,38(01):63-66.

[16] 陆峰,王刚,周井荣,等.3D腹腔镜手术联合加速康复外科在右半结肠癌中的应用[J].中国肿瘤外科杂志,2021,13(01):49-52.

[17] 王刚,周井荣,陆峰,等.阑尾炎合并肠套叠1例报告及文献回顾[J].基层医学论坛,2020,24(10):1470-1471.

（2）获得奖项：

连云港市政府特殊津贴；连云港市科技进步奖2项，新技术引进奖10余项；连云港市“五一劳动奖章”；连云港市“十大最美职工”；江苏省卫生系统省级青年岗位能手；连云港市“新长征突击手。