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研究生导师
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黄关宏

职务: 党委副书记、院长

简介

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1.社会兼职:

江苏省医学会肿瘤放射治疗委员会委员、江苏省抗癌协会理事、江苏省中西医结合学会肿瘤学分会委员、连云港市医学会放射肿瘤专业委员会副主任委员;

 

2.研究方向:

放射肿瘤学

 

3.主持/参与课题:

1)江苏省卫生厅项目:薏苡仁提取物在中晚期宫颈癌同步放化疗中的临床研究,2009--2012年,主持;

2)江苏省卫健委医学科研课题:CD44stHER-2表达相关性及对乳腺癌术后病人预后影响的研究,2017-2021年,主持;

3)连云港市卫生局重点人才课题:鼻咽癌细胞倍体性与鼻咽癌放射敏感性及预后关系的临床实验研究,2008-2010年,主持;

 

4.科技成果:

(1)已发表论文:

[1]Efficacy and safety of immune checkpoint inhibitors plus platinum-etoposide vs. platinum-etoposide in the first-line treatment of extensive-stage small cell lung cancer: a systematic review and a meta-analysis. Transl Cancer Res. 2024 Aug 31;13(8):4146-4158. doi: 10.21037/tcr-24-149. Epub 2024 Aug 19.

[2] Prognosis assessment of CD44+/CD24- in breast cancer patients: a systematic review and meta-analysis. Arch Gynecol Obstet. 2022 Oct;306(4):1147-1160. doi: 10.1007/s00404-022-06402-w. Epub 2022 Apr 18.

[3] Rapid, Simple, and Highly Specific Detection of Streptococcus pneumoniae With Visualized Recombinase Polymerase Amplification. Front Cell Infect Microbiol. 2022 Jun 2;12:878881. doi: 10.3389/fcimb.2022.878881.

[4]Design of GSH-Responsive Curcumin Nanomicelles for Oesophageal Cancer Therapy. Pharmaceutics. 2022 Aug 27;14(9):1802. doi: 10.3390/pharmaceutics14091802. PMID: 36145550; PMCID: PMC9503065.

[5] Development and Clinical Application of a Recombinase Polymerase Amplification-Lateral Flow Strip Assay for Detection of Carbapenem-Resistant Acinetobacter baumannii. Front Cell Infect Microbiol. 2022 May 11;12:876552. doi: 10.3389/fcimb.2022.876552.

[6] Efficacy and Safety of Programmed Cell Death 1 Inhibitor Monotherapy Versus Chemotherapy as Second-Line Treatment for Advanced Esophageal Cancer: A Meta-analysis and Systematic Review. Clin Ther. 2021 Nov;43(11):1997-2012. doi: 10.1016/j.clinthera.2021.09.018. Epub 2021 Nov 15.

[7] Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors for Advanced Non-small Cell Lung Cancer: A Network Meta-Analysis of Randomized Clinical Trials. Front Pharmacol. 2021 Oct 25;12:686876. doi: 10.3389/fphar.2021.686876.

[8] Anti-restriction protein KLcAHS enhances carbapenem resistanceMolecular Medicine Reports2020,212:903-908.

[9] Effect of CD44st and HER2 expression on the postoperative prognosis of breast cancer patientsOncoTargets and Therapy20191215):577-585IF:3.046.

[10] MiRNA-34a reversed TGF-β-induced epithelial -mesenchymal transition via suppression  of SMAD4 in NPC cellsBiomedicine & Pharmacotherapy2018106:216-224.

[11]HA-CD44st-TGF-β信号通路对乳腺癌 MCF-7细胞HER2表达及侵袭能力的影响,癌症进展,2019,177):796-775.

 

(2)获得奖项:

荣获省卫健委医学新技术引进二等奖2项,市卫健委医学新技术引进一等奖1项,市科技进步二、三等奖2项,连云港市“521高层次人才工程”培养对象,连云港市政府特殊津贴获得者,连云港市十佳科技工作者。